Publications by authors named "Kaveri Pandit"

Unlabelled: Acute intermittent porphyria (AIP) is autosomal dominant metabolic disorder of adulthood with limited case reports in children. Literature review from Western countries shows that most children present with non-specific gastrointestinal and neuropsychiatric symptoms with no family history. Moreover, the attacks are recurrent and precipitated by various factors (drugs/infection).

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Aim: The SARS-CoV-2 pandemic is characterised by multiple reports of paediatric multisystem inflammatory disease or multisystem inflammatory syndrome in children (MIS-C) with Kawasaki disease-like features often complicated by myocarditis, shock and macrophage activation syndrome. Certain clinical and laboratory markers may be used to identify high risk cases.

Methods: All sequentially admitted patients hospitalised between April 2020 and October 2020, who met the WHO case definition for MIS-C were included.

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Article Synopsis
  • Acute kidney injury (AKI) is a significant concern in children with COVID-19, with 22.8% of hospitalized patients developing it during a study in New Delhi, India.
  • The study analyzed 295 confirmed COVID-19 cases and found that AKI was more likely in patients with associated sepsis, nephrotic syndrome, and those requiring vasopressors or mechanical ventilation.
  • Mortality rates were notably high in children with AKI, especially in Stage 3, where 66.6% of affected patients died, indicating a need for early intervention in at-risk populations.
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