Inhibition of inducible nitric oxide production by Caryota urens and its active constituents umbelliferone and rutin.

Inducible Nitric Oxide Synthase (iNOS) is a key mediator in a variety of diseases, and thus it is interesting to discover new iNOS inhibitors. This study aimed to evaluate if the hydroalcoholic leaf extract of Caryota urens (CULHA) consisting of rutin and umbelliferone prevents inflammation in response to external stimuli. To demonstrate the therapeutic potential of CULHA against inflammatory diseases, nitric oxide production (NO) mediated by iNOS was evaluated.

A study on the GC-MS analysis of bioactive components and pancreato-protective effect of methanolic extract of Brassica oleracea L. var. botrytis.

The ever-increasing problem of pancreatitis due to alcohol abuse demands evaluation of novel drugs of plant origin. This study explores the therapeutic effects of the methanolic extract of Brassica oleraceae (MEBO) on ethanol and cerulein induced pancreatitis in rats. The MEBO was subjected to GC-MS and HPLC analysis.