Publications by authors named "Kaushal Shakya"

In this study, we have developed agar, a seaweed derived polysaccharide based green adsorbent for the removal of heavy metal ions (Pb, Cu, Cr and Cd) from multimetal solution. Porous cryogels of agar grafted with 3-aminopropyl triethoxysilane (APTES) were prepared by freeze-drying. The adsorption capacity and selectivity of the optimized APTES-agar cryogel for heavy metal ions (Cu, Cr, Pb, Cd) were investigated in multimetal solutions.

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Article Synopsis
  • Excessive bleeding from deep wounds, such as gunshots or stabs, poses a serious risk and highlights the need for improved hemostatic agents beyond current wound care solutions.
  • This research developed innovative cryogels made from agarose and polydopamine microspheres, which showed remarkable qualities including over 4000% absorption capacity and rapid blood clotting within 90 seconds in laboratory tests.
  • In animal models, the cryogels further proved their effectiveness, achieving clotting times of just 40 to 53 seconds, showcasing their potential as advanced wound dressings for better bleeding management.
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58S bioactive glass (BG) has effective biocompatibility and bioresorbable properties for bone tissue engineering; however, it has limitations regarding antibacterial, antioxidant, and mechanical properties. Therefore, we have developed BG biocomposites by reinforcing 58S BG with silver and ceria nanoparticles, which showed effective bactericidal properties by forming inhibited zones of 2.13 mm (against ) and 1.

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In this work, we have demonstrated agar and oxidized bacterial cellulose cryogels as a potential hemostatic dressing material. TEMPO-oxidized bacterial cellulose (OBC) was incorporated into the agar matrix, improving its mechanical and hemostatic properties. The oxidation of bacterial cellulose (BC) was evidenced by chemical characterization studies, confirming the presence of carboxyl groups.

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