Unlabelled: Alongside global climate change, many freshwater ecosystems are experiencing substantial shifts in the concentrations and compositions of salt ions coming from both land and sea. We synthesize a risk framework for anticipating how climate change and increasing salt pollution coming from both land and saltwater intrusion will trigger chain reactions extending from headwaters to tidal waters. Salt ions trigger 'chain reactions,' where chemical products from one biogeochemical reaction influence subsequent reactions and ecosystem responses.
View Article and Find Full Text PDFBismuth ferrite (BiFeO₃) is a multiferroic perovskite material with a narrow band gap (~2.1 eV), demonstrating significant potential as a photocatalyst for environmental remediation and sustainable energy applications. Its photocatalytic capabilities include dye degradation, air purification, wastewater treatment, and hydrogen generation, all driven by its ability to harness visible light.
View Article and Find Full Text PDFPresent study deals with the green fabrication of copper oxide nanoparticles (CuO NPs) employing cell-free aqueous extract of Cladophora glomerata (L.) Kuetz, freshwater algal species. The UV-visible, FTIR, XRD, FESEM, HRTEM, EDX, BET, XPS and Raman spectroscopic techniques were used to confirm and characterize the biosynthesized CuO NPs.
View Article and Find Full Text PDFAchieving the smallest crystallite/particle size of zinc oxide nanoparticles (ZnO NPs) reported to date, measuring 5.2/12.41 nm with () leaf extract, this study introduces a facile green synthesis.
View Article and Find Full Text PDFAutosomal hypophosphatemic rickets though a rare genetic disorder can lead to significant discomfort to the patient resulting in clinical deterioration and a poor quality of life. We describe a case of a 33-year-old woman G2P1001 at 6 weeks of gestation with complaints of myalgia and bony pains. Keeping her history of bony pains and fractures in mind, she was further evaluated.
View Article and Find Full Text PDFAmelogenesis imperfecta (AI) is a genetic disorder that affects both primary and permanent teeth. It primarily manifests as developmental disorders of enamel. The condition occurs independently of other systemic disorders and is caused by mutations in genes responsible for enamel formation, inherited in autosomal dominant, autosomal recessive or X-linked patterns.
View Article and Find Full Text PDFIntroduction: Hypospermatogenesis is a common histopathological subtype of non-obstructive azoospermia and is characterized by a decrease in the total number of germ cells within the seminiferous tubule as a result of spermatogenic failure. Determination of genetic factors before intracytoplasmic sperm injection can prevent the inheritance of these factors, as hypospermatogenesis patients gives high successful sperm retrieval rate. This study aimed to identify the structural variants associated with idiopathic hypospermatogenesis (iHS) by analyzing patient cohorts diagnosed with azoospermia using whole exome sequencing.
View Article and Find Full Text PDFObjectives: Attainment of the glycated hemoglobin (A1C) target of ≤7.0% is consistently low among those living with type 1 diabetes (T1D). We evaluated endocrinologists' acceptability and implementation of A1C targets.
View Article and Find Full Text PDFObjectives: Immune checkpoint inhibitors have revolutionized treatment of platinum-refractory advanced bladder cancer, offering hope where options are limited. Response varies, however, influenced by factors such as the tumor's immune microenvironment and prior therapy. Muscle-invasive bladder cancer (MIBC) is stratified into molecular subtypes, with distinct clinicopathologic features affecting prognosis and treatment.
View Article and Find Full Text PDFBackground: The role of repeat transurethral resection of bladder tumor (TURBT) for the management of nonmuscle invasive bladder carcinoma is debated, especially when initial resections include detrusor muscle. This study compares immediate second resection (additional deep biopsies in the same session) with standard restage TURBT performed 2-6 weeks post-initial TURBT to determine adequacy in detrusor muscle sampling and compare the disease rate at restage TURBT in both groups.
Material And Methods: A randomized trial was conducted at a tertiary care hospital, including patients aged ≥18 years undergoing TURBT with complete primary tumor resection.
Intrarenal hemangiomas lack concise clinicopathologic information, due to the predominance of single case reports and inclusion of other vascular neoplasms and hemangiomas of perirenal, hilar, and renal vein origin. Herein, in this multi-institutional study we evaluate clinicopathologic features of 39 intrarenal hemangiomas. The median age was 62 years (range = 27-94 years; 2:1 male to female ratio), with left-sided predominance (left = 21, right = 13; one case was bilateral).
View Article and Find Full Text PDFThis study aimed at comparing gingival depigmentation by locally injected vitamin C with surgical depigmentation, in terms of effectiveness and patient acceptability. Forty-two patients presenting with ethnicity-related hyperpigmentation were randomly divided into two groups, Group I ( = 21) was treated with locally injected vitamin C and Group II ( = 21) was treated by surgical depigmentation. The outcome was assessed using Gingival Pigmentation Index (GPI) and Skin Hyperpigmentation Index (SHI).
View Article and Find Full Text PDFPurpose: Objective information about the central auditory pathways in vestibular schwannoma can guide strategies for hearing rehabilitation and prognostication. This study aims to generate this information using diffusion tensor imaging (DTI).
Methods: This is a prospective observational single center study including 35 patients with vestibular schwannoma and 40 controls.
Immunoglobulin G4 (IgG4)-related disease is a rare immune-mediated fibro-inflammatory disorder with many clinical manifestations. Most commonly affected sites include the pancreas, salivary glands, kidneys, lachrymal glands, biliary tree, aorta and retroperitoneum; testicular involvement is a rare entity. This report describes a man in his 20s who presented with a persistent painless mass in his left testis.
View Article and Find Full Text PDFThe rapid advancements in machine learning have exacerbated the interconnect bottleneck inherent in binary logic-based computing architectures. An interesting approach to tackle this problem involves increasing the information density per interconnect, i.e.
View Article and Find Full Text PDFObjective: The objective of this study is to evaluate the diagnostic performance of urine cytology using The Paris System (TPS 2.0) in comparison with TPS 1.0, and the Four-Tier Reporting System (FTRS) of our institute for identifying high-grade urothelial carcinoma (HGUC).
View Article and Find Full Text PDFSoil carbon estimates in the Indian Himalayan region-a global climate change hotspot-primarily rely on the lossy wet oxidation method and predominantly focus on soil organic carbon (SOC), neglecting the soil inorganic carbon (SIC) component. Sensitive and holistic soil carbon estimates are crucial for effective policy planning. By incorporating eight major Central Himalayan forest types along a 3000 m elevational gradient, we report that the acidic Himalayan soil (surface soil pH: 4.
View Article and Find Full Text PDFObjectives: Patients with refractory chronic pain may be considered for spinal cord stimulation (SCS) as an interventional therapy. Studies have shown that psychiatric disorders are associated with worse outcomes. However, this relationship may not be understood by all healthcare professionals.
View Article and Find Full Text PDFThe occurrence of pancreatitis shortly after elective lumbar spine surgery in an adult is rare. We report a case of a 63-year-old female who developed, for the first time, acute pancreatitis within three days of elective lumbar (L) spine surgery that was performed for degenerative disk disease without significant deformity (i.e.
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