Human leukocyte antigens and multiple basal cell carcinomas.

This study presents data on human leukocyte antigen (HLA) phenotypes of 49 unrelated patients with multiple basal cell carcinomas (five or more BCC). Previous investigators noted an association with HLA-DR1 and a negative association with HLA-DR4. However, the previously found association was weak.

HLA phenotypes and multiple basal cell carcinomas.

Background: Previous investigators noted an association of multiple basal cell carcinomas (BCC) with certain HLA antigens; however, these findings were contradictory, and the associations were only weak.

Objective: The aim of the study was to objectify the previously found associations.

Methods: Serologic HLA typing for class I and class II antigens was performed in 49 unrelated patients with 5 or more BCCs.