[Is the recent decrease in cholesterolemia in the Czech Republic convincing evidence?].

Background: The objective of the study was to evaluate the 8-year trend of serum cholesterol levels in six districts of the Czech Republic, to assess whether the reduction of mean values of total cholesterol recorded during the period between 1985 and 1992 was convincing and to discuss possible causes and consequences of this development.

Methods And Results: Three cross-sectional surveys of risk factors were implemented in independent random 1% samples of the population aged 25-64 years. In 1985 1256 men (respondence rate 81.

[Serum lipid and lipoprotein levels in children in relation to their dietary habits and parental blood cholesterol].

In a group of 2000 Prague children aged 11-12 years the distribution of serum cholesterol levels was assessed. For further investigations 100 children with cholesterol levels above the 95th percentile (HYPER) were selected and 100 children with values between the 5th and 10th percentile (HYPO). Children and parents were subjected to detailed clinical and laboratory examination, in children the three-day dietary intake was assessed.

Cholesterolaemia in school-age children and hypercholesterolaemia aggregation in the family.

The distribution of cholesterol values was established in a group of 2,000 Prague children aged 11-12 years. Of these, 100 children with cholesterol values exceeding the 95th percentile (HYPER), and 100 children with values between the 5th and the 10th percentiles (HYPO) were selected for follow-up. In addition to a thorough clinical and laboratory examination in children and parents, three-day food consumption was registered in children.

The effect of stress on circadian rhythms.

The authors chose four types of intensive stress in man and show their effect on the circadian rhythms of selected parameters. Sleep deprivation reduces mean sideraemia and oscilation amplitudes. The morning rhythm maximum shifts to early morning hours.

[Vitamin C and psychomotor reactivity].

The effect of vitamin C on the activity of the brain was studied. In groups of workers well provided for with vitamin C allowances a reduced number of industrial traumas was noted, which can be attributed to a greater concentration of attention and better reactivity. This could be achieved by administering daily doses of 100-150 mg of vitamin C.