Publications by authors named "Katya Op De Beeck"

Background: Otosclerosis causes conductive, sensorineural and mixed hearing loss (CHL, SNHL, MHL) and tinnitus in young adults. It is best diagnosed on high-resolution CT (HRCT). Occasionally, patients presenting with SNHL and/or tinnitus may undergo temporal bone MRI as the first investigation.

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Objectives: Portal vein aneurysm is an unusual vascular dilatation of the portal vein. The etiology, diagnosis and management are ill-defined.

Methods: A case of a portal vein aneurysm complicated with complete thrombosis is presented with a literature review providing an overview of the etiology, clinical presentation and management.

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Background: Uterine fibroid embolization (UFE) is a minimally invasive imaging-guided treatment using radiation exposure.

Purpose: To compare the patients' radiation exposure during UFE before and after introduction of a new X-ray imaging platform.

Material And Methods: Forty-one patients were enrolled in a prospective, comparative two-arm project before and after introduction of a new X-ray imaging platform with reduced dose settings, i.

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Objective: To assess the clinical feasibility of whole-body diffusion-weighted MRI (WB-DWI/MRI) for diagnosis and prediction of complete tumour resection in patients with suspected recurrent ovarian cancer.

Methods: 51 females clinically suspected for ovarian cancer recurrence underwent 3-T WB-DWI/MRI in addition to contrast-enhanced CT. WB-DWI/MRI was assessed for detection of tumour recurrence, prediction of tumour extent and complete resection compared with CT.

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The 22q11 deletion syndrome (22q11DS), the most frequent microdeletion syndrome in humans, presents with a large variety of abnormalities. A common abnormality is hearing impairment. The exact pathophysiological explanation of the observed hearing loss remains largely unknown.

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A 23-year-old man presented with hypovolemic shock due to a lower gastrointestinal bleeding. Radiological and endoscopic investigation did not reveal the bleeding site. Emergency visceral angiography showed contrast extravasation at a right-sided branch of the superior mesenteric artery (SMA).

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We will describe a case of a patient diagnosed with a rare identity of a benign lesion, "reactive nodular fibrous pseudotumor" (RNFP). It is a tumor which preoperatively can present as a malignant tumor and is only reported in 19 cases. According to the very limited amount of information on this tumor in the literature it is mostly seen after trauma or intraperitoneal inflammation.

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Article Synopsis
  • Otosclerosis is a condition that leads to various types of hearing loss in adults, categorized mainly into fenestral and retrofenestral types.
  • High-resolution CT scans are preferred for diagnosing otosclerosis, particularly to examine the inner ear structures, while MRI is less useful for this purpose but can aid in pre-implant evaluations.
  • Treatment options differ based on the type, with surgical stapedectomy for fenestral cases and medical management with fluorides or cochlear implants for retrofenestral cases.
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Article Synopsis
  • This study assessed the effectiveness of changes in the apparent diffusion coefficient (ADC) at MRI one month post-transcatheter arterial chemoembolization (TACE) for liver cancer (HCC), comparing it to standard response criteria like RECIST and mRECIST.
  • Thirty-eight patients underwent MRI before and after TACE, with results showing that the ADC ratio was a strong predictor of progression-free survival (PFS), outperforming traditional criteria.
  • The findings suggest that the ADC ratio not only correlates well with tumor response but is also significantly linked to histopathologic necrosis, emphasizing its potential as a reliable predictor for patient prognosis.
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Objectives: To evaluate whole-body MRI with diffusion-weighted sequence (WB-DWI/MRI) for staging and assessing operability compared with CT and FDG-PET/CT in patients with suspected ovarian cancer.

Methods: Thirty-two patients underwent 3-T WB-DWI/MRI, (18) F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) and CT before diagnostic open laparoscopy (DOL). Imaging findings for tumour characterisation, peritoneal and retroperitoneal staging were correlated with histopathology after DOL and/or open surgery.

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A 5-year-old girl from Rwanda was referred to our pediatric oncology department with severe bilateral proptosis and a bloody, necrotic chemosis of the conjunctiva and infraorbital tissues. Furthermore, she presented with a left facial paresis, hemorrhagic gingiva, epistaxis, and bloody tears. There was a 3-month history of pancytopenia.

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Purpose: To evaluate diffusion-weighted imaging (DWI) for assessment of treatment response in head and neck squamous cell carcinoma (HNSCC) three weeks after the end of chemoradiotherapy (CRT).

Methods And Materials: Twenty-nine patients with HNSCC underwent magnetic resonance imaging (MRI) prior to and 3 weeks after CRT, including T(2)-weighted and pre- and postcontrast T(1)-weighted sequences and an echo-planar DWI sequence with six b values (0 to 1,000 s/mm(2)), from which the apparent diffusion coefficient (ADC) was calculated. ADC changes 3 weeks posttreatment compared to baseline (∆ADC) between responding and nonresponding primary lesions and adenopathies were correlated with 2 years locoregional control and compared with a Mann-Whitney test.

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Article Synopsis
  • Soft tissue sarcomas, particularly high-grade endometrial stromal sarcomas, are not commonly reported as complications during pregnancy.
  • A 28-year-old woman was diagnosed with a transperitoneal sarcoma while pregnant, and various analyses confirmed its high-grade nature.
  • Treatment options like surgery and chemotherapy are available during pregnancy but were not possible in this case, highlighting the need for individualized assessment of cancer treatment in pregnant patients.
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Objective: To evaluate diffusion-weighted (DWI) magnetic resonance imaging (MRI) for treatment prediction during chemoradiotherapy (CRT) of head and neck squamous cell carcinoma (HNC).

Methods: Thirty patients with HNC underwent echo-planar DWI and anatomical MRI before and 2 and 4 weeks into CRT. Patient follow-up lasted 2 years post-CRT.

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Article Synopsis
  • Sunitinib, a tyrosine kinase inhibitor, can cause thyroid dysfunction in cancer patients, often leading to hypothyroidism.
  • Patients with preexisting nodular thyroid issues may experience significant shrinkage of the thyroid during treatment, requiring long-term hormone replacement even after stopping the drug.
  • The exact reasons behind these changes are unclear, but the shrinkage could indicate permanent damage to the thyroid gland as a result of sunitinib treatment.
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Purpose: To evaluate the use of diffusion-weighted magnetic resonance imaging (DW-MRI) for nodal staging and its impact on radiotherapy (RT) planning.

Methods And Materials: Twenty-two patients with locally advanced head and neck squamous cell carcinoma underwent contrast-enhanced computed tomography (CT), as well as MRI (with routine and DW sequences) prior to neck dissection. After topographic correlation, lymph nodes were evaluated microscopically with prekeratin immunostaining.

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  • The study evaluated the effectiveness of diffusion-weighted magnetic resonance imaging (DW-MRI) in distinguishing hepatocellular carcinoma (HCC) from benign lesions in cirrhotic patients, comparing it to traditional dynamic contrast-enhanced MRI.
  • Results showed that while signal intensity ratios differed significantly between malignant and benign lesions for all measured b-values, there was no notable difference in apparent diffusion coefficients.
  • DW-MRI at the b600 value demonstrated higher sensitivity (95.2%) and specificity (82.7%) for detecting malignant lesions versus conventional MRI, making it particularly useful for identifying small HCC tumors under 2 cm.
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