Objectives: The aim of our study was to assess the adherence to labelling and international guidelines for antifungal prescribing.
Methods: A retrospective study was performed in intensive care units in addition to the oncology and haematology department, which covered 70% of antifungal consumption at Hautepierre Hospital, Strasbourg, France. On reviewing medical charts, the antifungal prescription was examined in relation to the recommendations of indication, dosage, risk of drug-drug interactions and, where appropriate, antifungal susceptibility testing.
Objectives: To describe and estimate the rate of breakthrough invasive mould diseases (IMD) in patients receiving caspofungin.
Methods: Retrospective, non-interventional study conducted in three University Hospitals.
Results: Nineteen breakthrough infections have been identified including 13 aspergillosis, 2 mucormycosis, a fusariosis, a Hormographiella aspergillata infection and 2 possible IMD.