Hepatocellular carcinoma in otherwise sonographically normal liver.

Purpose: Hepatocellular carcinoma (HCC) on normal liver is very rare. The goal of this study was to determine the clinical manifestations and the role of ultrasonography (US) in the diagnosis of HCC arising in normal liver.

Methods: The clinical data and US findings in 12 cases of surgically resected HCC in normal liver were retrospectively analyzed.