Shaping the curve from the microscopic transsphenoidal to the endoscopic endonasal approach for the sellar region.

Objective: This study aimed to investigate the limitations, barriers, and complications in the early transition from the microscopic transsphenoidal approach (MTA) to the endonasal endoscopic approach (EEA) to the skull base in our institution.

Methods: Technical challenges, as well as clinical features and complications, were compared between MTA, EEA, and mixed cases during the early surgical curve.

Results: The period from the early learning curve was 1 year until the EEA protocol was used routinely.