Publications by authors named "Katsuyuki Obara"

Secondary bone marrow involvement of non-Hodgkin's lymphoma (NHL) is relatively common. However, primary isolated bone marrow involvement in NHL which was successfully treated and remains in complete remission (CR) for a long-term duration without any relapse is extremely rare. We herein report a patient of primary bone marrow diffuse large B cell lymphoma (PBML/DLBCL) who presented a prolonged high-grade fever and systemic purpura due to severe thrombocytopenia.

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Article Synopsis
  • - A 75-year-old male was diagnosed with type II enteropathy-associated T cell lymphoma (EATL) after presenting with abdominal discomfort and abnormal CT findings, leading to chemotherapy treatment that initially resulted in complete remission.
  • - Eighteen months later, he experienced rapid mental decline, and brain imaging revealed masses that were confirmed to be necrotic tumors through biopsy, indicating a central nervous system relapse of EATL.
  • - Despite receiving high-dose chemotherapy, the patient succumbed to the disease, highlighting the poor prognosis associated with EATL and the need for more effective treatment options.
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Waldenström's macroglobulinemia (WM) is an indolent chronic lymphoproliferative disorder within the spectrum of lymphoplasmacytic lymphoma (LPL), characterized by a proliferation of plasmacytoid lymphocytes and the production of monoclonal IgM. Although, peripheral neurologic complications commonly occurs due to hyperviscosity in WM, central nervous system (CNS) involvement is very rare. Herein, we present the case of a 67-year-old man who initially presented with progressive visual loss and was diagnosed as WM/LPL with a very aggressive clinical course.

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Primary malignant lymphoma of the cauda equina is an extremely rare disease. Previously, there have been only 12 reported cases of malignant lymphoma of the cauda equina, and most cases relapsed early in the clinical course. So, the optimal treatment strategy for this condition has not been established yet and the prognosis is thought to be poor.

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