Glutathione S-transferase (GST) exhibits antidotal effects on numerous drugs, including platinum-based antineoplastic drugs. Furthermore, () polymorphism is associated with peripheral neuropathy. In the present study, it was determined whether can predict adverse events associated with platinum-based antitumor agent-induced peripheral neuropathy among Japanese patients.
View Article and Find Full Text PDFGan To Kagaku Ryoho
November 2017
A 79-year-old woman presented with a chief complaint of a palpated tumor on her right axilla. The right breast tumor size was 18mm and the axillary lymph node size was 30 mm, as detected with ultrasonography. Pathological findings indicated the presence of an ER(-), Pg R(-), HER2-negative apocrine carcinoma.
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