Background: Despite numerous studies of peripancreatic inflammatory fluid collection (PIFC) that report on the relevance of the drain amylase concentration (D-AMY), early prediction using this assay is problematic. This study aimed to investigate the clinical significance of measuring the D-AMY at 3 h after gastrectomy (POD0) for gastric cancer.
Methods: This retrospective analysis included consecutive patients who underwent gastrectomy combined with peripancreatic lymph node dissection.
N6-methyladenosine (mA), the most abundant internal RNA modification, serves a critical role in cancer development. However, the clinical implications of mA in hepatocellular carcinoma (HCC) remain unclear. The present study sought to reveal the potential roles of mA readers, which recognize mA, in HCC.
View Article and Find Full Text PDFBackground/aim: N6-Methyladenosine (m6A), the most abundant internal modification of RNA, plays a critical role in cancer development. However, the clinical implications of mA in hepatocellular carcinoma (HCC) remain unclear.
Materials And Methods: We analyzed 177 HCC and paired noncancerous liver tissues from patients who underwent hepatectomy according to global mA quantification and expression of mA demethylases fat mass and obesity-associated protein (FTO) and alpha-ketoglutarate-dependent dioxygenase alkB homolog 5 (ALKBH5).
Objectives: Postoperative pancreatic fistula (POPF) is the most threatening complication after pancreatectomy. This study aimed to directly assess pancreatic fatty infiltration with preoperative computed tomography (CT) imaging and to investigate whether a preoperative analysis of patient variables, including CT characteristics and clinical factors, can predict POPF.
Methods: We enrolled 150 consecutive patients who underwent curative pancreatectomy.
A novel biosensor for determination of d-amino acids (DAAs) in biological samples by using an electrode based on immobilization of a thermostable d-Proline dehydrogenase (d-Pro DH) within an agar gel membrane was developed. The electrode was simply prepared by spin-coating the agar solution with the d-Pro DH on a glassy carbon (GC) electrode. An electrocatalytic oxidation current of 2,6-dichloroindophenol (DCIP) was observed at -100mV vs.
View Article and Find Full Text PDF