Publications by authors named "Katsuhiro Nishimura"

Background: This study aimed to develop a prediction model for intestinal perforation from meconium ileus (MI) based on findings from plain X-ray images.

Methods: Very low birth weight (VLBW) infants with MI hospitalized in two tertiary centers between 2011 and 2022 were included in this study. We retrospectively reviewed clinical parameters and assessed plain X-ray images from 0 to 5 days of age.

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Purpose: To elucidate the clinical significance of sarcopenia in children with neuroblastic tumors (NTs).

Methods: We conducted a retrospective observational study and analyzed the z-scores for height, body weight, body mass index, and skeletal muscle index (HT-z, BW-z, BMI-z, and SMI-z) along with the clinical characteristics of 36 children with NTs. SMI-z was calculated from 138 computed tomography scans at diagnosis, during treatment, and at follow-up.

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  • This study explored how nephrostomies affect total renal function (TRF) and split renal function (SRF) in patients with pelvic tumors that cause upper urinary tract obstruction (UUTO).
  • Researchers analyzed data from patients treated between 2000 and 2022, comparing those who received nephrostomies to those who did not.
  • Results indicated that nephrostomy improved estimated glomerular filtration rate (eGFR) in treated patients, while those without the procedure showed no improvement, suggesting that nephrostomies may enhance renal outcomes in this context.
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  • A pilot study was conducted to assess the effectiveness of indocyanine green-guided near-infrared fluorescence (ICG-NIRF) imaging in predicting long-term testicular atrophy after testicular torsion (TT) surgery.
  • The study included 12 patients who underwent TT surgery, with testicular blood flow evaluated using ICG-NIRF imaging and categorized based on fluorescence detection.
  • Results showed a 100% correlation between lack of ICG-NIRF signals and subsequent testicular atrophy, suggesting that this imaging technique may help inform surgical decisions for TT patients.
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Unlabelled: Invariant natural killer T (iNKT) cells play an essential role in antitumor immunity by exerting cytotoxicity and producing massive amounts of cytokines. iNKT cells express invariant T-cell receptors (TCR) to recognize their cognate glycolipid antigens such as α-galactosylceramide (α-GalCer) presented on CD1d. We recently reported that iNKT cells recognize CD1d-negative leukemia cell line K562 in a TCR-dependent manner.

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Purpose: This study evaluated the abdominal aortic diameter in high-risk neuroblastoma (NB) patients and the risk of aortic narrowing following intensive treatment.

Methods: We measured the aortic diameter at four specific levels of the abdominal aorta (diaphragmatic crus, celiac axis, and the root of the superior (SMA) and inferior (IMA) mesenteric arteries) on contrast CT scans. The control group consisted of 56 children with non-oncologic disorders, while the NB group included 35 patients with high-risk abdominal NB.

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  • The study aimed to understand how physical measurements (like height and weight) relate to acute appendicitis in infants compared to school-age children.
  • Researchers analyzed data from 73 infants and 362 school-age children hospitalized for appendicitis between 2004 and 2018, focusing on their anthropometric Z-scores.
  • They found that infants with appendicitis were generally larger than school-age children in terms of height and weight, but this trend didn't apply to the severity of the appendicitis (perforated vs. non-perforated cases).
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