Publications by authors named "Katsuhiko Machida"
Objective: The present study was conducted to clarify the effects of ultra-marathon (ultra long-term aerobic exercise in which people run long distances) on the brain; examine the issue of central fatigue; verify the serotonin hypothesis of exercise-induced brain fatigue, and ascertain relationships between central fatigue and oxidative stress.
Methods: Subjects consisted of 15 individuals (12 men, 3 women) who ran continuously for 24 h. Mean age was 44 +/- 9 years (range, 31 approximately 64 years).
Article Synopsis
- The laboratory conducted an investigation on malaria detection using three methods: May Giemsa staining (MG), acridine orange staining (AO), and the NOW ICT antigen detection kit (Ag).
- Out of 207 requests, 15 patients tested positive for malaria, with cases primarily linked to Africa and Southeast Asia, and a high correlation in detection rates between the methods used (94.4% and 96.9%).
- The findings indicated that both MG and the antigen detection kit had comparable sensitivity, suggesting that using the antigen detection kit could be a reliable option for routine testing in laboratories.
A 1.4 kb positive regulatory element (ETA(exp)) that controls staphylococcal exfoliative toxin A (sETA) transcription was cloned from Staphylococcus aureus. ETA(exp) is located upstream of the cloned 5.
View Article and Find Full Text PDFThe isothermal and chimeric primer-initiated amplification of nucleic acids (ICAN) is a new isothermal DNA amplification method composed of exo Bca DNA polymerase, RNaseH and DNA-RNA chimeric primers. We developed the simultaneous detection system for Chlamydia trachomatis/Neisseria gonorrhoeae DNA, combined with luminescence detection by a probe hybridization. In the performance tests, this system was able to detect 10 to 100 copies of C.
View Article and Find Full Text PDFSleep-disordered breathing (SDB) causes fluctuation of the RR interval. However, the details are uncertain. We studied the characteristics of sleep-related heart rate variation (HRV) in congestive heart failure (CHF) patients with SDB.
View Article and Find Full Text PDFCheyne-Stokes respiration is common in congestive heart failure patients and causes cyclical fluctuation of the RR interval. We studied the characteristics of apnea-related heart rate variability (apnea HRV) and the relation between apnea HRV and oxygen desaturation was examined. Ambulatory electrocardiograms and data on respiration (oronasal flow, tracheal sounds, abdominal wall movement and oxygen saturation) were simultaneously recorded by a multi-channel digital recorder for 16 congestive heart failure patients (10 men and 6 women; mean age, 68 +/- 13 years).
View Article and Find Full Text PDFThe detection kits for Bacillus anthracis, an isoform of host prion and Coxiella burnetii, using genetic technology are still not generalized. For B. anthracis target genes for detection would be genes of toxins.
View Article and Find Full Text PDFApnea-related heart rate variability and its clinical utility in congestive heart failure outpatients.
Ann Noninvasive Electrocardiol
April 2002
Background: Cheyne-Stokes breathing (CSB) is an abnormal cyclical pattern of respiratory fluctuations observed during sleep in congestive heart failure (CHF) of poor prognosis. We examined the clinical usefulness of CSB screening using the heart rate variability (HRV) data from the ambulatory electrocardiogram.
Methods: We monitored ambulatory electrocardiograms and respiration simultaneously in 86 heart disease patients of both sexes, aged 57 +/- 1 years.