Publications by authors named "Katrine Brodersen"

Article Synopsis
  • Bariatric surgeries like sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) improve glucose tolerance in type 2 diabetes (T2D) primarily by enhancing insulin secretion and glucose effectiveness rather than significantly changing insulin sensitivity.
  • In a study involving 16 individuals (9 RYGB and 7 SG), patients displayed similar weight loss and notable increases in insulin secretion and glucose effectiveness two months post-surgery.
  • The surgeries also resulted in a greater increase in hepatic insulin extraction compared to healthy controls, while GLP-1 response increased and GIP levels remained unchanged.
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Background: Atrial fibrillation is the most common cardiac arrhythmia and a major global health burden. Updated trends in the epidemiology of atrial fibrillation or flutter (AF) are needed.

Methods: Using the Danish Heart Statistics, we investigated nationwide trends 2009-2018 in incidence rate and prevalence of AF according to age as well as age-standardized incidence rate (ASIR) and prevalence (ASP) of AF according to sex, ethnicity, educational level, and area of residence.

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Aim: Bariatric surgery improves insulin sensitivity and glucose tolerance in obese individuals with type 2 diabetes (T2D), but there is a lack of data comparing the underlying metabolic mechanisms after the 2 most common surgical procedures Roux-en-Y gastric bypass surgery (RYGB) and sleeve gastrectomy (SG). This study was designed to assess and compare the effects of RYGB and SG on fuel metabolism in the basal state and insulin sensitivity during a two-step euglycemic glucose clamp.

Materials And Methods: 16 obese individuals with T2D undergoing either RYGB ( = 9) or SG ( = 7) were investigated before and 2 months after surgery, and 8 healthy individuals without obesity and T2D served as controls.

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Severe systemic inflammation is associated with nausea, loss of appetite, and delayed gastric emptying, which increases hospitalization admission length and mortality rate. There is a lack of human controlled studies exploring gastric emptying rates and underlying mechanisms during inflammatory conditions. We aimed to investigate if systemic inflammation in young men delays gastro-intestinal transit times, lowers motility, and affects gastrointestinal hormone secretion.

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Acute aortic syndrome is a group of pathogenic conditions including aortic dissection, intramural haematoma, penetrating ulcer and aortic aneurysm. The syndrome is a challenging clinical diagnosis because the symptoms are numerous and diverse with similarity to other more common conditions. Delayed diagnosis and treatment can be fatal.

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Intussusception of the appendix is a rare condition with an incidence of approximately 0.01%. In adults, the lead point for the intussusception is most frequently endometriosis, whereas in children, acute inflammation of the appendix is usually the cause (76%).

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