Publications by authors named "Katrina R Beckett"
Importance: Approximately 20% of thyroid nodules display indeterminate cytology. Molecular testing can refine the risk of malignancy and reduce the need for diagnostic hemithyroidectomy.
Objective: To compare the diagnostic performance between an RNA test (Afirma genomic sequencing classifier) and DNA-RNA test (ThyroSeq v3 multigene genomic classifier).
Article Synopsis
- Molecular testing is increasingly used to avoid unnecessary surgeries for indeterminate thyroid nodules, but there's no direct comparison between different testing methods.
- This study compared the Afirma Gene Expression Classifier (GEC) and ThyroSeq v2 in a group of patients with indeterminate thyroid nodules, finding that ThyroSeq v2 had higher specificity and allowed more patients to avoid surgery.
- The results indicate that while ThyroSeq v2 performed better than GEC, further research is needed to evaluate the long-term effectiveness and comparison with other molecular diagnostic techniques.
Iodinated and gadolinium-based contrast media are used on a daily basis in most radiology practices. These agents often are essential to providing accurate diagnoses, and are nearly always safe and effective when administered correctly. However, reactions to contrast media do occur and can be life threatening.
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