Publications by authors named "Katrina Ducena"
Immun Ageing
November 2024
Article Synopsis
- miR-146a regulates inflammation and is involved in high-fat diet-induced hypothalamic senescence, but its role has not been fully explored.
- Wild-type mice on a high-fat diet showed increased body weight, cognitive decline, and senescence markers in the brain, while knocking out miR-146a exacerbated these effects.
- Treatment with elocalcitol improved health outcomes in HFD WT mice by upregulating miR-146a and mitigating senescence effects, highlighting its therapeutic potential, which was not effective in miR-146a knockout mice.
