Publications by authors named "Katrin Wanner"
Background: Starting combination antiretroviral therapy (cART) during primary human immunodeficiency virus type 1 (HIV-1) infection results in a smaller HIV-1 latent reservoir, reduced immune activation, and less viral diversity compared to starting cART during chronic infection. We report results of a 4-year study designed to determine whether these properties would allow sustained virological suppression after simplification of cART to dolutegravir (DTG) monotherapy.
Methods: EARLY-SIMPLIFIED is a randomized, open-label, noninferiority trial.
Article Synopsis
- - The study focused on whether the IMX-BVN-3 classifier can effectively identify COVID-19 patients who may have bacterial infections, helping to decide on antibiotic treatment.
- - Results showed that 91.9% of the 111 COVID-19 patients were classified as very likely or possibly having a viral infection, with about 94% being unlikely to have a bacterial infection.
- - Among patients identified as possibly or very likely having a bacterial infection, 85.7% had actual bacterial coinfections or superinfections, indicating IMX-BVN-3's potential usefulness in managing COVID-19 cases.