Publications by authors named "Katrin Huesker"
Background/objective: Endoprostheses might fail due to complications such as implant loosening or periprosthetic infections. The surface topography of implant materials is known to influence osseointegration and attachment of pathogenic bacteria. Laser-Induced Periodic Surface Structures (LIPSS) can improve the surface topography of orthopedic implant materials.
View Article and Find Full Text PDFThe gadolinium-based contrast agent DOTA-Gd is clinically used in combination with local anesthetics for direct magnetic resonance arthrography. It remains unclear whether gadolinium uptake into cartilage is influenced by co-administration of bupivacaine or ropivacaine and whether DOTA-Gd alters their chondrotoxicity. Gadolinium quantification of chondrogenic spheroids revealed enhanced gadolinium uptake after simultaneous exposure to local anesthetics.
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- * Using advanced synchrotron X-ray technology, the researchers analyzed the multi-elemental composition of peri-implant tissues, finding that cobalt (Co) and chromium (Cr) particles are present, while titanium (Ti) particles predominantly consist of titanium dioxide.
- * The findings suggest that Co and Cr can accumulate in the bone marrow and affect the surrounding bone structure, highlighting the need for reevaluating the long-term impacts of metal implants on human health.
Delayed type hypersensitivity (DTH) reactions are considered infrequent complications in arthroplasty, but have been recognized to be associated with devastating morbidity and substantial decrease in quality of life of affected patients. Chronic inflammation of artificial joints and associated loss of peri-implant bone often require revision surgery. Methods for the diagnosis of implant-related DTH are available but infrequently considered to the full extent.
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