Publications by authors named "Katrin Echtler"
Platelets modulate the process of cancer metastasis. However, current knowledge on the direct interaction of platelets and tumor cells is mostly based on findings obtained in vitro. We addressed the role of the platelet fibrinogen receptor glycoprotein IIb (integrin αIIb) for experimental melanoma metastasis in vivo.
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- Deep vein thrombosis (DVT) is a serious condition that can lead to heart problems and death.
- Scientists created a new mouse model that helps them study how DVT happens, which is similar to what happens in humans.
- The research shows that certain immune cells (like monocytes and neutrophils) play a key role in starting and spreading DVT by working together with platelets, which helps the blood clotting process.
The ductus arteriosus (DA) is a fetal shunt vessel between the pulmonary artery and the aorta that closes promptly after birth. Failure of postnatal DA closure is a major cause of morbidity and mortality particularly in preterm neonates. The events leading to DA closure are incompletely understood.
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