Publications by authors named "Katrin Christine Asciutto"
Background/aim: Vulva cancer surgery is associated with a high level of morbidity mostly due to wound healing disorders in the inguinal region following lymphadenectomy. Our aim is to evaluate the feasibility of negative pressure wound therapy (NPWT) using the PICO™ device in groin wounds after lymphadenectomy.
Patients And Methods: The groins of twenty patients who underwent bilateral lymph node dissection were dressed with the PICO™ device.
Background: During 2013 and 2016 the region of Skåne, Sweden started to analyse human papillomavirus (HPV) and cytology in postmenopausal women 60-65 years of age. Our aim was to evaluate high-risk (HR) HPV mRNA testing for the triage of HPV DNA-positive postmenopausal women with normal cytology.
Methods: A total of 271 women, 60-65 years of age, underwent liquid-based cytology (LBC) and HPV testing by using the HR-HPV DNA MGP-PCR-Luminex assay.
Background/aim: Cervical cancer is associated with poorer diagnosis among the elderly and pap-smear screening has a lower sensitivity. Self-sampling for detection of high-risk human papillomavirus (hr-HPV) may be an alternative screening method. The aim of this study was to analyze the response rate to vaginal HPV self-sampling and the HPV mRNA prevalence among women 69-70 years.
View Article and Find Full Text PDFAim: To compare the clinical performance of human papillomavirus (HPV) mRNA and DNA assays in postmenopausal women.
Materials And Methods: A total of 5,925 postmenopausal women were tested with cytology and the Luminex HPV DNA assay. High risk-HPV-positive women with benign cytology underwent a complimentary HPV mRNA assay (APTIMA).
Background: In order to increase coverage in the organized cervical screening program, self-sampling with HPV analyses has been suggested.
Objectives: The aim was to compare human papillomavirus (HPV) mRNA detection in vaginal and urine self-collected samples with clinician-taken cervical samples and the corresponding clinician-taken histological specimens.
Study Design: Self-collected vaginal, urine and clinician-taken cervical samples were analyzed from 209 women with the Aptima mRNA assay (Hologic Inc, MA, USA).
Background/aim: To compare human papillomavirus (HPV) DNA detection in self-collected vaginal and urine samples with clinician-taken cervical samples in relation to histology.
Materials And Methods: Self-collected vaginal, urine and clinician-taken cervical samples were analyzed from 218 women with the Cobas 4800 HPV test (Roche Molecular Diagnostics).
Results: The sensitivity for detection of HPV in the vaginal self-sampling test was 96.
Follow up with HPV test and cytology as test of cure, 6 months after conization, is reliable.
Acta Obstet Gynecol Scand
November 2016
Introduction: Human papillomavirus (HPV) infection is an objective marker with a high sensitivity for finding cervical dysplasia. The objective of the current study is to investigate whether HPV testing, combined with liquid-based cytology, is reliable as a test of cure after the loop electrical excision procedure (LEEP).
Material And Methods: The LEEP was performed in 330 women for excision of cervical dysplasia.
Aim: To evaluate women with atypical glandular cells (AGC) or adenocarcinoma in situ (AIS) on cytology.
Patients And Methods: Population-based data of cervical smears taken between 2008-2012 were analyzed.
Results: Cancer was diagnosed in 107 out of 199 patients (54%) with AGC or AIS; 30 with cervical adenocarcinoma and 77 with endometrial cancer.