A validated stability-indicating UPLC method for the determination of impurities in Maraviroc.

Maraviroc is an antiretroviral drug in the CCR5 receptor antagonist class, which is used in the treatment of HIV. Maraviroc has six impurities. A novel, stability-indicating reversed-phase ultra-performance liquid chromatography (RP-UPLC) method has been developed for the quantitative determination of maraviroc in active pharmaceutical ingredients, along with its six impurities.