Publications by authors named "Katja Ruhnke"
Article Synopsis
- Cisplatin-based chemotherapy has been used for 40 years to treat a specific type of cancer called germ cell tumors (GCT), but some patients don't respond well and have a part called yolk-sac tumor (YST) that doesn't get better.
- Researchers studied ways to overcome this resistance by looking at proteins and genes, and they tested a new treatment called CLDN6-ADC that seems to work better on cancer cells than healthy ones.
- The study found that certain drugs targeting specific pathways could be promising for treating YST, and they discovered several factors that contribute to why some tumors resist treatment.
