Fall-risk-increasing adverse reactions-is there value in easily accessible drug information? A case-control study.

Purpose: The individual fall risk of a patient is often multifactorial. Polymedication contributes to an additional risk of fall-risk-increasing adverse reactions (FRIARs). Previous studies have not sufficiently investigated the complexity facing prescribers when balancing the therapeutic benefits of individual drugs against their potential fall risk.

Quantitative determination of phenolic diterpenes in rosemary extracts. Aspects of accurate quantification.

Practical challenges related to accurate quantification of carnosic acid (CA), carnosol (CAR) and other phenolic diterpenes in extracts of rosemary leaves (Rosmarinus officinalis L.) are presented and discussed. Primary standard material of CA is isolated from rosemary extracts by preparative chromatography with a purity of 98% or higher.