Epidemiological characteristics of invasive meningococcal disease in the Split-Dalmatia County 1996-2010.

The aim of this paper is to present epidemiological features of reported patients with invasive meningococcal disease in the Split-Dalmatia County in the period from January 1996 to December 2010. During the 15-year period (1996-2010), a total of 119 patients were reported to have invasive meningococcal disease, yielding a mean annual incidence rate of 1.7/100,000 inhabitants.

Common variant in myocilin gene is associated with high myopia in isolated population of Korcula Island, Croatia.

Aim: To study the association between genetic variants in myocilin and collagen type I alpha 1 genes and high myopia in an isolated island population.

Methods: A total of 944 examinees from the genetic epidemiology study conducted on the island of Korcula, Croatia, were included in the study. We selected 2 short nucleotide polymorphisms (SNP) available in our genome-wide scan set of SNPs that were previously associated with high myopia and used them to replicate previous claims of possible association.