Publications by authors named "Katie K Ly"
Article Synopsis
- Computer-vision and machine-learning techniques are being utilized to evaluate mouse behavior in Alzheimer's disease models, using a method called variational animal motion embedding (VAME).
- Significant changes in behavior were observed in Alzheimer’s models, such as age-related differences and increased randomness in actions.
- Intervention by blocking certain neuroinflammation processes largely mitigated these behavioral changes, highlighting the impact of neuroinflammation on spontaneous behavior in Alzheimer's disease.
Progress in understanding long COVID and developing effective therapeutics is hampered in part by the lack of suitable animal models. Here we used ACE2-transgenic mice recovered from Omicron (BA.1) infection to test for pulmonary and behavioral post-acute sequelae.
View Article and Find Full Text PDFAnkle foot orthoses (AFOs) are designed to improve gait for individuals with neuromuscular conditions and have also been used to reduce energy costs of walking for unimpaired individuals. AFOs influence joint motion and metabolic cost, but how they impact muscle function remains unclear. This study investigated the impact of different stiffness AFOs on medial gastrocnemius muscle (MG) and Achilles tendon (AT) function during two walking speeds.
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