Comparing the in vitro effects of MGO Manuka honey and tea tree oil on ocular Demodex viability.

Purpose: To compare the in vitro antiparasitic effects of MGO Manuka honey and tea tree oil against ocular Demodex.

Methods: Fifty-two viable Demodex mites were acquired from the epilated eyelashes of 9 participants with blepharitis and symptomatic dry eye. Viable mites were randomised to one of five treatment groups: cyclodextrin-complexed and uncomplexed Manuka Honey, 100% and 50% tea tree oil, and no treatment.