Unlabelled: We aim to define the optimal white cell count threshold that correlates with a clinically significant urinary tract infection, as there is insufficient data exploring this in the adult population. We conducted a retrospective cohort study at the Royal Melbourne Hospital analyzing urine samples collected over 6 months in 2022. Urinary tract infection (UTI) was defined as the presence of symptoms (dysuria, urgency, frequency, flank pain, or loin to groin pain) and isolation of a uropathogen with colony counts greater than 10 CFU/L.
View Article and Find Full Text PDFObjectives: We aimed to describe the characteristics of Clostridioides difficile infection (CDI) in cancer patients, analysing risk factors for 90-day recurrence and attributable mortality.
Methods: Retrospective analysis on all CDI episodes from 2020 to 2022 in three Australian hospitals and one Spanish hospital. Logistic regression analyses were performed.
Curr Opin Infect Dis
December 2022
Purpose Of Review: This review provides an update on recent findings about the clinical and microbiological characteristics of Staphylococcus lugdunensis .
Recent Findings: European Committee on Antimicrobial Susceptibility Testing (EUCAST) and Clinical and Laboratory Standards Institute (CLSI) differ in their methodology and breakpoints for the detection of penicillin and oxacillin resistance in S. lugdunensis .
Objective: Test whether a single e-learning session can improve empathy and communication across pre-registration and postgraduate physiotherapy students.
Methods: Design: Two-phase sequential mixed methods study. Phase 1: Pilot randomised control trial.
Disseminated histoplasmosis (DH), an endemic mycosis caused by the dimorphic fungus Histoplasma capsulatum, is a life-threatening infection in immunocompromised hosts. A patient with newly-diagnosed human immunodeficiency virus (HIV) infection presented with a violaceous, raised, indurated, pruritic rash over the face, arms and trunk on a background of significant weight loss, fevers with sweats, diarrhoea and worsening shortness of breath. His CD4+ T cell count was 14 cells/µl (12%).
View Article and Find Full Text PDFWe investigated the in vitro activity of a novel fifth-generation cephalosporin-tazobactam combination, ceftolozane-tazobactam against , the etiological agent of melioidosis. Using both disc diffusion and minimum inhibitory concentration (MIC) strip techniques against 56 clinical isolates and an national collection of type cultures (NCTC) strain, the MIC to ceftolozane-tazobactam was found to be between 0.75 and 4 mcg/mL.
View Article and Find Full Text PDFBackground: Until recently, carbapenemase (KPC)-producing Enterobacteriaceae were rarely identified in Australia. Following an increase in the number of incident cases across the state of Victoria, we undertook a real-time combined genomic and epidemiological investigation. The scope of this study included identifying risk factors and routes of transmission, and investigating the utility of genomics to enhance traditional field epidemiology for informing management of established widespread outbreaks.
View Article and Find Full Text PDFThis systematic review examines the methods and results of recent studies reporting clinical criteria able to identify patients with bacteremia who are at very low risk of endocarditis. We searched PubMed, EMBASE, and the Cochrane Collaboration CENTRAL database for articles published after March 1994 using a combination of MeSH and free text search terms for AND bacteremia AND endocarditis. Studies were included if they presented a combination of clinical and microbiological criteria with a negative likelihood ratio of ≤0.
View Article and Find Full Text PDFThe medical sector presents a unique opportunity for identification and service to victims of human trafficking. In this article, we describe local and site-specific efforts to develop an intervention tool to be used in an urban hospital's emergency department in the midwestern United States. In the development of our tool, we focused on both identification and intervention to assist trafficked persons, through a largely collaborative process in which we engaged local stakeholders for developing site-specific points of intervention.
View Article and Find Full Text PDFHealth disparities among low-income individuals remain a significant problem. A number of social determinants are associated with adverse health outcomes. Medical-legal partnerships address legal concerns of low-income individuals to improve health and wellness in adults and children.
View Article and Find Full Text PDFMedical-legal partnerships (MLPs) integrate legal services into the health care setting to resolve legal issues that have a negative impact on patient health. These partnerships between attorneys and health care professionals have traditionally focused on physicians. Despite early success and expansion of the MLP model, the literature is only beginning to explore the significant role that social workers can play in an MLP's development, process, and success.
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