Publications by authors named "Katie C T Riciluca"
Article Synopsis
- CAPA is a common complication in severe COVID-19 patients, but its diagnosis is difficult, often relying on specific tests and clinical criteria.
- In a study of 15 COVID-19 patients in Brazil, 17 cases of Aspergillus spp. were isolated, leading to diagnoses of probable CAPA in 5 patients based on specific tests and symptoms.
- Despite treatment with antifungal agents like voriconazole in most cases, the mortality rates were high, highlighting the need for greater awareness and better diagnostic practices for CAPA.
Infectious diseases are among the major causes of death in the human population. A wide variety of organisms produce antimicrobial peptides (AMPs) as part of their first line of defense. A peptide from Acanthoscurria rondoniae plasma, rondonin-with antifungal activity, a molecular mass of 1236 Da and primary sequence IIIQYEGHKH-was previously studied (UniProt accession number B3EWP8).
View Article and Find Full Text PDFA strategy that has been gaining increased application for the study of the conformation, dynamics, orientation, and physicochemical properties of peptides is labeling with the paramagnetic amino acid TOAC. This approach was used to gain a deeper understanding on the mechanism of action of the antimicrobial peptide tritrpticin (TRP3). TRP3 was labeled with TOAC at the N-terminus (prior to V, TOAC-TRP3) or internally (replacing P, TOAC-TRP3).
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