Publications by authors named "Katia Vanessa Gutierrez-Quiroz"
Article Synopsis
- The study aimed to assess lung function and asthma control in patients with Non-Exacerbated Respiratory Disease (N-ERD) over three years, following GINA guidelines.
- At baseline, N-ERD patients showed better lung function and required lower doses of inhaled corticosteroids compared to traditional asthma patients, who relied more on oral corticosteroids.
- By the end of the follow-up, the lung function of traditional asthma patients improved significantly, leading to similar asthma control levels in both groups, but one-third of N-ERD patients continued needing additional medications to maintain control.
Objetive: To describe the phenotype of DRESS syndrome induced by antituberculosis drugs.
Methods: Descriptive study, withdrawn from the review of the records of patients with DRESS syndrome, identified in the interconsultation of the Department of Research in Immunogenetics and Allergy, of the Insti-tuto Nacional de Enfermedades Respiratorias (INER) Ismael Cosío Villegas, among 2014 and 2020. Frequency analysis was performed.
The discovery of the mechanism underlying allergic disease, mouse models of asthma, and bronchoscopy studies provided initial insights into the role of Th2-type cytokines, including interlukin (IL)-4, IL-5 and IL-13, which became the target of monoclonal antibody therapy. Omalizumab, Benralizumab, Mepolizumab, Reslizumab, and Tezepelumab have been approved. These biologicals have been shown to be good alternative therapies to corticosteroids, particularly in severe asthma management, where they can improve the quality of life of many patients.
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