Publications by authors named "Katia Schwichtenberg"
Objective: Persisting neurological symptoms after COVID-19 affect up to 10% of patients and can manifest in fatigue and cognitive complaints. Based on recent evidence, we evaluated whether cerebral hemodynamic changes contribute to post-COVID syndrome (PCS).
Methods: Using resting-state functional magnetic resonance imaging, we investigated brain perfusion and oxygen level estimates in 47 patients (44.
Post-COVID-19 syndrome is a serious complication following SARS-CoV-2 infection, characterized primarily by fatigue and cognitive complaints. Although first metabolic and structural imaging alterations in Post-COVID-19 syndrome have been identified, their functional consequences remain unknown. Thus, we explored the impact of Post-COVID-19 syndrome on the functional connectome of the brain providing a deeper understanding of pathophysiological mechanisms.
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- Post-COVID syndrome causes severe long-term fatigue and cognitive issues following COVID-19, with 47 out of 50 patients showing moderate to severe fatigue around 7.5 months post-infection.
- Imaging studies detected structural changes in the thalamus and basal ganglia, indicating potential brain-related causes for the fatigue, which also correlated with factors like sleep quality and anxiety.
- Unlike fatigue in multiple sclerosis, the severity of post-COVID fatigue did not relate to the severity of the original COVID-19 illness, suggesting distinct underlying mechanisms.