Publications by authors named "Katia Rivera Fabian"

Introduction: Endocrine paraneoplastic syndromes (ePNS) are caused by malignant cells that induce hormonal alterations unrelated to the tissue of origin of the neoplasm. The aim of this manuscript is to review the pathophysiology, diagnosis, and treatment of endocrine paraneoplastic syndromes (ePNS).

Areas Covered: We searched the PubMed/Medline, Embase, and Scielo databases, including 96 articles.

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Introduction: Methimazole is an antithyroid drug known to cause hematological toxicity, including agranulocytosis and, very rarely, pancytopenia. We herein present a case of a patient with Graves' Disease (GD) who developed methimazole-induced pancytopenia.

Case Report: A 53-year-old Peruvian woman with GD, initially treated with methimazole 20 mg BID, experienced odynophagia, fever, and malaise after 37 days of treatment.

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Article Synopsis
  • Thyrolipomatosis is an extremely rare condition characterized by the infiltration of fatty tissue in the thyroid gland, with only about 30 cases documented globally; it can occur alongside malignant neoplasms but never previously reported with tongue cancer.
  • A 44-year-old female patient was diagnosed with an infiltrative tongue mass and underwent surgery, revealing thyrolipomatosis in her thyroid along with the need to remove part of her tongue and lymph nodes.
  • Despite the initial treatment, the patient experienced a recurrence of squamous cell carcinoma and complications that led to septic shock and her subsequent death, highlighting the potential risks of coexisting benign and malignant conditions in the thyroid and tongue.
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Hypothyroidism is an endocrine disorder whose management raises many challenges in clinical practice. Its standard treatment is levothyroxine (LT4). The goal of the treatment is to normalize signs and symptoms, as well as to achieve thyroid-stimulating hormone (TSH) concentrations within the reference range, on an individual basis.

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