Publications by authors named "Katia Regina Assuncao Borges"

Article Synopsis
  • - Omega-3 fatty acids, particularly EPA and DHA, provide significant health benefits, and research focused on enhancing these acids in fish oil through low-cost methods involving lipase enzymes.
  • - A specific lipase, Lipase F2, derived from the fungus F. solani, was produced using submerged fermentation and demonstrated strong enzyme activity, stability at pH 8.0, and resilience to various conditions.
  • - Lipase F2 effectively enriched fish oil with omega-3 fatty acids, achieving high concentrations of DHA and EPA, making it a cost-effective alternative to commercial enzymes for potential use in the food and pharmaceutical industries.
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This study explores a nanoemulsion formulated with açaí seed oil, known for its rich fatty acid composition and diverse biological activities. This study aimed to characterise a nanoemulsion formulated with açaí seed oil and explore its cytotoxic effects on HeLa and SiHa cervical cancer cell lines, alongside assessing its antioxidant and toxicity properties both in vitro and in vivo. Extracted from fruits sourced in Brazil, the oil underwent thorough chemical characterization using gas chromatography-mass spectrometry.

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Açaí, Mart., is a native plant from the Amazonian and is rich in several phytochemicals with anti-tumor activities. The aim was to analyze the effects of açaí seed oil on colorectal adenocarcinoma (ADC) cells.

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Problem Of Research: Candida spp. biofilms are complex microbial communities that have been associated with increasing resistance to clinically available antifungal drugs. Hence, novel pharmacological approaches with ability to inhibit biofilm formation have been investigated.

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Açaí ( Mart) is an Amazon plant with many biological properties. Previous report of this group evidenced autophagy induction after treatment with açaí seed extract in MCF-7 breast cancer cell lines by acridine orange assay. The aim of this study was to evaluate the ultrastructural changes induced by açaí seed extract in MCF-7 breast cancer cell lines.

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Article Synopsis
  • This study examined how green propolis extract affects the sticking and biofilm formation of Candida species on dental materials.
  • Using high-performance liquid chromatography, researchers identified 15 compounds in green propolis extract, primarily flavonoids, and assessed yeast cell adhesion on materials over time.
  • Results showed that while some Candida species formed moderate to very strong biofilms on materials like steel and resin, green propolis extract effectively inhibited adhesion and biofilm development at a concentration of 2.5 μg/mL, highlighting its potential antifungal properties.
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Article Synopsis
  • Environmental issues are worsening due to population growth, with soilborne fungi playing a crucial role in ecosystem balance, particularly in the Jansen Lagoon State Park in São Luís, Brazil, which faces pollution from sewage dumping.
  • Monthly soil samples were taken and analyzed using a specific technique to isolate filamentous fungi present in the park's soil.
  • The dominant isolated fungal genera were identified, with the most prevalent species being noted, suggesting their potential use as biological indicators of pollution and their capacity for bioremediation in this impacted area.
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Introduction: Candida parapsilosis is one of the main species that is able to adhere to forming biofilms on inert materials. Adhesion is the first step towards the colonization and invasion of host cells during the infectious process. Among the infections, vulvovaginal candidiasis is increasingly common.

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