Publications by authors named "Kati Jaatinen"

Background: Surgery, needle fasciotomy, and collagenase injection are used to treat Dupuytren contracture. The treatment decision requires balancing initial morbidity and costs of surgery against its potential long-term benefits over needle fasciotomy and collagenase.

Objective: To compare the effectiveness of surgery, needle fasciotomy, and collagenase injection at 3 months and 2 years (secondary time points of the trial).

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Background: Carpal tunnel syndrome (CTS) is a compression neuropathy of the median nerve at the wrist. Surgery is considered when symptoms persist despite the use of non-surgical treatments. It is unclear whether surgery produces a better outcome than non-surgical therapy.

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Objectives: To identify the evidence gaps that exist regarding the efficacy or effectiveness of hand surgery.

Setting: A scoping review. We systematically searched MEDLINE, Embase and CENTRAL databases to identify all hand surgical randomised controlled trials from inception to 7 November 2020.

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Article Synopsis
  • - The study aimed to evaluate the internal validity of hand surgical randomized controlled trials (RCTs) by examining their reporting and methods, highlighting that poor practices can lead to inaccurate estimations of treatment benefits or risks.
  • - A comprehensive review of 207 RCTs revealed significant issues, with high or unclear risks of bias in various domains like selection (72%), performance (93%), and detection (88%), which could affect the reliability of their findings.
  • - Notably, studies with a high or unclear risk of selection bias showed larger effect sizes, but overall, there was an observable improvement in reducing selection bias over time, suggesting that adherence to better methodologies could enhance the quality of future trials.
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Carpal tunnel syndrome (CTS) is the most common upper extremity compression neuropathy. Non-operative interventions are usually the first-line treatments, and surgery is reserved for those that do not achieve a satisfactory symptom state by non-operative means. This narrative review summarizes the current evidence regarding the efficacy of orthoses, corticosteroid injections, platelet-rich plasma injections, Kinesio taping, neurodynamic techniques, gabapentin, therapeutic ultrasound, and extracorporeal shockwave therapy in people with CTS.

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