Publications by authors named "Kathy M Tran"

Article Synopsis
  • * A study reviewed records of AML patients, identifying 21 who displayed SS characteristics; notable findings included a significant presence of -5/del(5q) karyotype and FLT3 gene mutations.
  • * The research highlighted that 52% of SS cases were classified as AML with myelodysplasia-related features, indicating potential underlying genetic and cytogenetic factors in these patients.
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Fibroblast growth factors (Fgfs) and their receptors (Fgfr) are expressed in the developing and adult CNS. Previous studies demonstrated a decrease in cortical interneurons and locomotor hyperactivity in mice with a conditional Fgfr1 deletion generated in radial glial cells during midneurogenesis (Fgfr1(f/f);hGfapCre+). Here, we report earlier and more extensive inactivation of Fgfr1 in neuroepithelial cells of the CNS (Fgfr1(f/f);NesCre+).

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Infants born premature experience hypoxic episodes due to immaturity of their respiratory and central nervous systems. This profoundly affects brain development and results in cognitive impairments. We used a mouse model to examine the impact of hypoxic rearing (9.

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