Health State Utilities for Acute Myeloid Leukaemia: A Time Trade-off Study.

Objectives: Acute myeloid leukaemia (AML) is an aggressive haematological cancer associated with significant humanistic impact. The current study assessed how the general public in the United Kingdom (UK) values AML health states.

Methods: The composite time trade-off (cTTO) methodology was employed to elicit health state utilities in AML.

Interviewing to develop Patient-Reported Outcome (PRO) measures for clinical research: eliciting patients' experience.

Patient-reported outcome (PRO) measures must provide evidence that their development followed a rigorous process for ensuring their content validity. To this end, the collection of data is performed through qualitative interviews that allow for the elicitation of in-depth spontaneous reports of the patients' experiences with their condition and/or its treatment. This paper provides a review of qualitative research applied to PRO measure development.