Publications by authors named "Kathy Ding"
Article Synopsis
- Bronchopulmonary dysplasia (BPD) is a chronic lung disease mainly affecting premature infants, linked to issues like poor lung development and harmful exposure to high oxygen levels, leading to fibrosis and pulmonary hypertension (PH).
- The study investigates the effects of Nintedanib (NTD), an anti-fibrotic drug, on lung health in newborn rats exposed to high oxygen, aiming to see if it can improve lung function and prevent PH.
- Results showed that hyperoxia significantly harmed lung structure and function, but it is unclear if NTD could help rectify these issues without adverse effects on developing lungs.
Acute kidney injury (AKI) is common in patients, causes systemic sequelae, and predisposes patients to long-term cardiovascular disease. To date, studies of the effects of AKI on cardiovascular outcomes have only been performed in male mice. We recently demonstrated that male mice developed diastolic dysfunction, hypertension and reduced cardiac ATP levels versus sham 1 year after AKI.
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- Acute kidney injury (AKI) is linked to increased long-term heart-related health issues as shown by recent studies.
- A 1-year study on male mice indicated that AKI results in ongoing problems with heart metabolism, leading to issues like high blood pressure and heart dysfunction.
- Treatment with ITF2357 helped maintain normal heart function and blood pressure but did not prevent kidney scarring following AKI.