Relative importance of factors affecting corneal hysteresis measurement.

Purpose: To evaluate the relative influences of several demographic, ocular, and systemic parameters on corneal hysteresis (CH).

Methods: This is a prospective, observational, cross-sectional study using subjects recruited from consecutive Albuquerque VAMC eye clinic patients. We classified eligible subjects as primary open-angle glaucoma (POAG), ocular hypertension, glaucoma suspect, or normal.

Factors influencing intermethod agreement between goldmann applanation, pascal dynamic contour, and ocular response analyzer tonometry.

Purpose: To examine factors that influence intraocular pressure (IOP) measurement agreement between Goldmann applanation (GAT), Ocular Response Analyzer (ORA), and Pascal Dynamic Contour tonometers (DCT).

Patients And Methods: In subjects who were diagnosed with primary open-angle glaucoma, ocular hypertension, glaucoma suspect, and normal, we used ORA, DCT, and GAT to obtain corneal hysteresis (CH), corneal resistance factor (CRF), ocular pulse amplitude, and 4 IOP values (ORA-IOPcc; ORA-IOPg; DCT-IOP; and GAT-IOP.) We also obtained corneal curvature, corneal thickness, axial length, retinal nerve fiber layer thickness, visual field parameters, diabetes diagnostic status, and topical IOP-lowering treatment data.

Repeatability and reproducibility for intraocular pressure measurement by dynamic contour, ocular response analyzer, and goldmann applanation tonometry.

Purpose: To evaluate and compare the intraocular pressure measurement variability between Goldmann applanation tonometry (GAT), Pascal dynamic contour tonometry (DCT), and ocular response analyzer (ORA) tonometry.

Methods: Subjects were prospectively recruited from consecutive Albuquerque VA Medical Center eye clinic patients that were previously diagnosed with ocular hypertension, glaucoma suspect, primary open-angle, or normal pressure glaucoma. Two sets of intraocular pressure measurements (3-4 ORA, 2 DCT, and 2 GAT) were obtained approximately 15 minutes apart.

Ocular Response Analyzer in subjects with and without glaucoma.

Purpose: The Ocular Response Analyzer (ORA) is a newly introduced tonometer that uniquely measures and then integrates corneal biomechanical data into its intraocular pressure (IOP) estimates in an effort to improve accuracy of IOP assessment. This study was devised to investigate whether ORA-derived IOP and corneal biomechanical variables might be useful in discriminating between subjects with and without primary open-angle glaucoma (GLC).

Methods: All patients seen in the Albuquerque VAMC eye clinic over a 10-week period who demonstrated acceptable ORA signal profiles were retrospectively identified.

Clinical comparison of pascal dynamic contour tonometry and goldmann applanation tonometry in asymmetric open-angle glaucoma.

Purpose: To investigate and compare the relationships between glaucomatous visual field loss and intraocular pressure (IOP) as measured by both Pascal dynamic contour tonometry (DCT) and Goldmann applanation tonometry (GAT).

Patients And Methods: All primary open-angle glaucoma and normal tension glaucoma patients seen between July 2005 and June 2006 with at least 2 sets of good-quality, bilateral DCT and GAT measurements were retrospectively identified. Additional inclusion criteria required that all subjects had repeatable, asymmetric glaucomatous visual field loss that corresponded with asymmetric glaucomatous optic neuropathy.

Central corneal thickness and normal tension glaucoma: a cross-sectional study.

Background: Recently published evidence has identified thinner central corneal thickness (CCT) as a strong predictive factor for the conversion from ocular hypertension (OHT) to primary open-angle glaucoma (POAG). The association between CCT and development of normal-tension glaucoma (NTG), however, is less clear. Accordingly, we designed this cross-sectional study to further explore the relationship between CCT and NTG.

Relationship between central corneal thickness and severity of glaucomatous visual field loss in a primary care population.

Background: Although the ability of central corneal thickness (CCT) to predict development of primary open-angle glaucoma has become increasingly well recognized, the ability of CCT to predict severity of glaucoma remains uncertain. This study was designed to expand the available knowledge about the relationship between CCT and glaucoma severity.

Methods: Retrospective identification of all patients with a clinical diagnosis of either primary open angle glaucoma (POAG) or ocular hypertension who were seen from September 2002 through May 2003 at the Albuquerque VA Medical Center eye clinic was completed.

The relationship between central corneal thickness-adjusted intraocular pressure and glaucomatous visual-field loss.

Background: Although measurement of central corneal thickness (CCT) is increasingly becoming an important component of glaucoma risk analysis, significant controversy exists regarding the benefit of calculating a corrected intraocular pressure (IOP) value from measured IOP and CCT data.

Methods: Three hundred forty-four male subjects were identified from a VA eye clinic with one of the following clinical diagnoses: ocular hypertension (OHT), primary open-angle glaucoma (POAG), normal tension glaucoma (NTG), and normal tension glaucoma suspect (NTGS). Using one eye per subject, multivariate logistic regression and correlational analyses were performed to determine relationships between glaucomatous visual-field loss and several glaucoma risk factors, including adjusted IOP values.