Publications by authors named "Kathy A Robert"
Purpose: The objective of this scientometric analysis was to recognize the top 100 cited articles on 'Male infertility and Antioxidants' and analyze its publication characteristics.
Materials And Methods: The Scopus database was used to retrieve related articles and the top 100 identified based on citation rate.
Results: The articles were published in 56 journals between 1995 and 2019 with a median (interquartile range) citation score of 17 (5-62).
Article Synopsis
- Assisted reproductive technologies (ART) are key for addressing severe male infertility, and this study analyzes two decades of research trends in this field from 2000 to 2019 using scientometric data.
- A total of 2,148 publications were examined, with the Cleveland Clinic Foundation being the leading contributor, and stable research trends were observed in ART over the years.
- The study highlighted density gradient centrifugation and intracytoplasmic sperm injection as the most common techniques, with azoospermia being the primary clinical focus and pregnancy rates being the main outcome of interest.
Reactive oxygen species (ROS) are produced in significant amounts by spermatozoa and leucocytes. They are necessary to carry out various physiological functions such as sperm capacitation, hyperactivation, acrosome reaction, sperm-zona binding and cellular signalling pathways. Oxidative stress (OS) results when the ROS levels overwhelm the available antioxidant reserve.
View Article and Find Full Text PDFSperm DNA Fragmentation: A New Guideline for Clinicians.
World J Mens Health
October 2020
Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases of spermatogenesis, which imparts compaction and protects the genetic content. Testicular (defective maturation and abortive apoptosis) and post-testicular (oxidative stress) mechanisms are implicated in the etiology of sperm DNA fragmentation (SDF), which affects both natural and assisted reproduction.
View Article and Find Full Text PDFUnraveling the role of reactive oxygen species and associated oxidative stress (OS) in male reproduction is one of the key areas of male reproductive research. This article illustrates the scientific landscape of OS in male reproductive research over the past several decades (1941-2018) using a scientometric approach. Scientometric data (articles per year, authors, affiliations, journals, and countries) on OS related to male reproduction were retrieved from the Scopus database and analyzed for each decade.
View Article and Find Full Text PDFBoth oxidative stress (OS) and reductive stress (RS) are the two extreme facets of redox imbalance that can have deleterious effects on sperm function. However, there is a lack of information on the physiological range of oxidation-reduction potential (ORP). The aim of this study was to investigate the effect of OS and RS on functions and associated molecular changes in normal spermatozoa in order to establish the physiological range of ORP.
View Article and Find Full Text PDFBackground: This article describes the research trends in sperm DNA fragmentation (SDF) over the past 20 years (1999-2018) using a scientometric approach.
Methods: A stepwise approach was adopted to retrieve scientometric data (articles per year, authors, affiliations, journals, countries) from Scopus and analyze the publication pattern of SDF with reference to key areas of research in the field of Andrology.
Results: A total of 2121 articles were retrieved related to SDF.