Corrigendum: Sarcopenic Obesity in Facioscapulohumeral Muscular Dystrophy.

[This corrects the article DOI: 10.3389/fphys.2020.

Baroreflex sensitivity in facioscapulohumeral muscular dystrophy.

Facioscapulohumeral muscular dystrophy (FSHD), a common form of muscular dystrophy, is caused by a genetic mutation that alters DUX4 gene expression. This mutation contributes to significant skeletal muscle loss. Although it is suggested that cardiac muscle may be spared, people with FSHD have demonstrated autonomic dysregulation.

Exercise Intolerance in Facioscapulohumeral Muscular Dystrophy.

Purpose: Determine 1) if adults with facioscapulohumeral muscular dystrophy (FSHD) exhibit exercise intolerance and 2) potential contributing mechanisms to exercise intolerance, specific to FSHD.

Methods: Eleven people with FSHD (47 ± 13 yr, 4 females) and 11 controls (46 ± 13 yr, 4 females) completed one visit, which included a volitional peak oxygen consumption (V̇O2peak) cycling test. Breath-by-breath gas exchange, ventilation, and cardiovascular responses were measured at rest and during exercise.

Menstrual phase does not influence ventilatory responses to group III/IV afferent signaling in eumenorrheic young females.

Estrogen can reduce sympathetic activity, but its effects on minute ventilation (V) with group III/IV afferent activation remain unclear. This study examined the influence of estrogen on V during lower-extremity exercise with group III/IV activation. Females completed two identical visits in follicular and ovulatory menstrual phases.

Resting metabolic rate in adults with facioscapulohumeral muscular dystrophy.

This study aimed to determine whether resting metabolic rate (RMR) is altered in adults with facioscapulohumeral muscular dystrophy (FSHD). Eleven people with FSHD (51 ± 12yrs, 2 females) and 11 controls (48 ± 14 yrs, 2 females) completed 1 visit, including 30-minutes of indirect calorimetry and dual-energy X-ray absorptiometry (DXA) scanning. RMR was calculated from resting oxygen consumption/carbon dioxide production; regional/whole-body fat mass and lean mass were collected from the DXA scan.

Sarcopenic Obesity in Facioscapulohumeral Muscular Dystrophy.

Background: Sarcopenic obesity has been observed in people with neuromuscular impairment, and is linked to adverse health outcomes. It is unclear, however, if sarcopenic obesity develops in adults with facioscapulohumeral muscular dystrophy (FSHD).

Methods: The purpose of this study was to determine if adults with FSHD meet criteria for sarcopenic obesity (appendicular lean mass index (ALMI) scores of < 7.