Histoplasmosis presenting as pneumoperitoneum in patients with acquired immune deficiency syndrome: case reports and review of the literature.

Histoplasmosis is a rare, but important, disease process in patients with the acquired immune deficiency syndrome (AIDS). Initially reported in this patient population in 1982, over 100 cases of histoplasmosis have been reported throughout the United States. Most of these patients present with disseminated disease.

Compliance and outcomes: do African Americans with advanced breast cancer fare worse?

Among women with advanced breast cancer, African Americans are thought to have a higher mortality rate than Caucasian. A number of factors, including intrinsic tumor biology, have been postulated for this survival difference. If similar treatment were offered, and actually completed, is there a survival difference? The objectives of this study were to determine 1) if the treatment regimens offered to African Americans and Caucasian were the same, 2) when treatment was offered, was compliance a factor, and 3) if the patients were compliant, was the outcome different? A retrospective review of 72 charts of patients with advanced stage breast cancer from 1988-present at our institution and an affiliated hospital was performed.

Body and distal pancreatectomy for metastatic renal cell carcinoma: case report and review of the literature.

Renal cell carcinoma is known for its unpredictable behavior. Spontaneous regression of metastatic disease has been reported; and patients have been known to survive for years with metastatic disease. Reports of long intervals between nephrectomy and metastatic disease are common.

TLK1B is elevated with eIF4E overexpression in breast cancer.

Introduction: The overexpression of eukaryotic initiation factor 4E (eIF4E), a critical component of the "RNA helicase" necessary for the initiation of protein synthesis of mRNAs with long 5' prime untranslated regions (5'UTRs), can result in malignant transformation. In a prospective study on breast cancer outcome of women with stage I to III disease, eIF4E overexpression was an independent predictor of cancer recurrence (RR = 7.3, CI = 1.

The sestamibi scan as a preoperative screening tool.

Sestamibi scan is generally recognized in the literature to play a role in the imaging of parathyroid adenoma. Most institutions quote sensitivities ranging from 80 to 100 per cent. There is still a question as to whether patients need preoperative localization studies.

Management of Fournier's gangrene: an eleven year retrospective analysis of early recognition, diagnosis, and treatment.

Fournier's gangrene is an infectious necrotizing fasciitis of the perineum and genital regions. It is a synergistic infection caused by a mixture of aerobic and anaerobic organisms. The mortality rate from this infection ranges from 0 to 67 per cent.