Publications by authors named "Kathryn Roy"

Article Synopsis
  • The study examines adverse drug reactions (ADRs) reported by individuals who received COVID-19 vaccinations, comparing those with a history of SARS-CoV-2 infection to those without, across different vaccine brands and doses.
  • Conducted from February 2021 to February 2023, it included 4,788 vaccinees and found that those with previous infections reported higher ADRs after the first and booster doses, but lower ADRs after the second dose.
  • Overall, while the frequency of serious ADRs was low, the study highlights the variation in reported reactions based on prior infection history and the type and timing of vaccine doses.
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Objective: To describe the clinical features of a cohort of individuals with stiff person syndrome spectrum disorders (SPSD) and identify potential early predictors of future disability.

Background: There is a need to better understand the full spectrum of clinical and paraclinical features and long-term impact of SPSD.

Design/methods: Observational study from 1997 to 2022 at Johns Hopkins.

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Article Synopsis
  • Many people with asthma are also obese, which can make their asthma harder to control.
  • The study involved 102 participants across the U.S., most of whom were African American females, and showed that many had poorly controlled asthma and were not very active.
  • It's important to help people in underserved communities by improving their ability to exercise while also addressing both their asthma and obesity issues.
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Background: The blood feeding poultry red mite (PRM), Dermanyssus gallinae, causes substantial economic damage to the egg laying industry worldwide, and is a serious welfare concern for laying hens and poultry house workers. In this study we have investigated the temporal gene expression across the 6 stages/sexes (egg, larvae, protonymph and deutonymph, adult male and adult female) of this neglected parasite in order to understand the temporal expression associated with development, parasitic lifestyle, reproduction and allergen expression.

Results: RNA-seq transcript data for the 6 stages were mapped to the PRM genome creating a publicly available gene expression atlas (on the OrcAE platform in conjunction with the PRM genome).

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