Cortical activation for adolescent-onset minor depression and major depressive disorder: an fNIRS study.

Background: While depression is increasing worldwide, some patients are diagnosed as having Major Depressive Disorder (MDD), but others are diagnosed with minor depression, however, the potential neuro mechanism is unknown.

Methods: Sixty-two patients with minor depression, 44 adolescents with MDD and 54 healthy adolescents participated in this study. Functional near-infrared spectroscopy (fNIRS), both HAMD and HAMA data were collected from all of the participants.

Resting-state brain activity in Chinese boys with low functioning autism spectrum disorder.

Background: This study aimed to explore the resting-state fMRI changes in Chinese boys with low functioning autism spectrum disorder (LFASD) and the correlation with clinical symptoms.

Methods: The current study acquired resting-state fMRI data from 15 Chinese boys with LFASD and 15 typically developing (TD) boys to examine the local brain activity using the regional homogeneity (ReHo) and amplitude of low-frequency fluctuation (ALFF) indexes; the researchers also examined these measures and their possible relationships with clinical symptoms using the autism behavior checklist.

Results: Results indicated that boys with LFASD exhibited increased ReHo in the right precuneus and inferior parietal gyrus (IPG), increased ALFF in right middle temporal gyrus, angular gyrus and IPG.

Resting-state functional changes in the precuneus within first-episode drug-naive patients with MDD.

Background: Major depressive disorder (MDD) is a leading psychiatric disorder that has a lack of biomarkers for a diagnosis.

Purpose: The objective of this study was to examine the structural and functional change in the precuneus within first-episode drug naive patients with MDD.

Methods: Thirty-two first episode drug-naive patients with MDD and thirty healthy controls (HCs) were recruited in this study; the structural MRI and fMRI data were collected using the 3.

Intelligence profiles of Chinese school-aged boys with high-functioning ASD and ADHD.

Purpose: This study aimed to explore the intelligence profiles of Chinese school-aged boys with high-functioning autism spectrum disorder (HFASD) and attention-deficit/hyperactivity disorder (ADHD). Additionally, differences in intelligence quotient (IQ) between the HFASD group and the ADHD group were examined.

Patients And Methods: Thirty-two boys with HFASD, 58 boys with ADHD, and 39 typically developing (TD) boys aged 6-16 years participated in this study.