Publications by authors named "Kathryn R Piper"
Background: The opportunistic bacterium Escherichia coli can invade normally sterile sites in the human body, potentially leading to life-threatening organ dysfunction and even death. However, our understanding of the evolutionary processes that shape its genetic diversity in this sterile environment remains limited. Here, we aim to quantify the frequency and characteristics of homologous recombination in E.
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- Bacteria found in bats produce valuable secondary metabolites and show significant genomic diversity based on the species of bat and cave location they inhabit.
- A study analyzed the genomes of 132 bacterial isolates from 11 species of insectivorous bats across six cave sites in Arizona and New Mexico, revealing that bacterial isolates from the same bat species or cave had higher genomic similarity.
- Despite the ecological influence on genomic similarity, the distribution of biosynthetic gene clusters (BGCs) was not limited to specific bat species or sites, highlighting the rich diversity of BGCs present across various bat species which could inform future natural product research.
is a ubiquitous commensal and opportunistic bacterial pathogen that can cause a wide gamut of infections, which are exacerbated by the presence of multidrug-resistant and methicillin-resistant . is genetically heterogeneous and consists of numerous distinct lineages. Using 558 complete genomes of , we aim to determine how the accessory genome content among phylogenetic lineages of is structured and has evolved.
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