Plasticity of cardiovascular function in snapping turtle embryos (Chelydra serpentina): chronic hypoxia alters autonomic regulation and gene expression.

Reptile embryos tolerate large decreases in the concentration of ambient oxygen. However, we do not fully understand the mechanisms that underlie embryonic cardiovascular short- or long-term responses to hypoxia in most species. We therefore measured cardiac growth and function in snapping turtle embryos incubated under normoxic (N21; 21% O₂) or chronic hypoxic conditions (H10; 10% O₂).

The paclitaxel-eluting stent in percutaneous coronary intervention: part I: background and clinical comparison to bare metal stents.

The development of coronary artery stents that release (elute) a drug locally into the diseased vasculature has revolutionized the practice of interventional cardiology. These devices were designed to minimize the incidence of in-stent restenosis that may occur with bare metal stents. The paclitaxel-eluting stent is the most recent drug-eluting stent approved for use in the United States and is a bare metal stent coated with paclitaxel that is gradually released from the stent into the vessel wall with undetectable systemic concentrations of the drug.