Gender differences in expectations and outcomes for total shoulder arthroplasty: a prospective cohort study.

Background: Gender has an impact on the expectations and the outcomes of orthopedic procedures. The data examining the effect of gender on total shoulder arthroplasty (TSA) are limited but suggest that women may have worse outcomes. We performed a prospective comparison between men and women with regard to expectations and midterm functional outcomes for TSA.

Galeazzi semitendinosus tenodesis for patellofemoral instability in skeletally immature patients.

Background: Numerous surgical treatments have been described to address subluxation or dislocation of the patella, but many are not suitable for the skeletally immature patient, as they risk injury to the proximal tibial physis or tibial tubercle apophysis. The Galeazzi semitendinosus tenodesis is a soft-tissue reconstruction technique designed to stabilize the patella without altering the femoral or the bony structures about the knee. We sought to determine if this semitendinosus tenodesis is a safe and effective treatment for patellofemoral instability in skeletally immature patients.

Mutations in genes encoding fast-twitch contractile proteins cause distal arthrogryposis syndromes.

The distal arthrogryposes (DAs) are a group of disorders characterized by multiple congenital contractures of the limbs. We previously mapped a locus for DA type 2B (DA2B), the most common of the DAs, to chromosome 11. We now report that DA2B is caused by mutations in TNNI2 that are predicted to disrupt the carboxy-terminal domain of an isoform of troponin I (TnI) specific to the troponin-tropomyosin (Tc-Tm) complex of fast-twitch myofibers.