Type, content, and triggers for self-injurious thoughts and behaviors in autistic youth and their disclosure to caregivers.

Self-injurious thoughts and behaviors are high among autistic youth, yet research most often relies on caregiver reports and does not include youth perspectives. Relatedly, specific characteristics of self-injurious thoughts and behaviors (e.g.

Machine Learning Prediction of Self-Injurious Outcomes in Adolescents by Sexual and Gender Identity.

Objective: Sexual and gender minority adolescents face elevated rates of self-injurious thoughts and behaviors (SITBs) relative to peers, yet fewer studies have examined risk in these youth, and reasons for higher risk remain unclear. Modeling SITBs using traditional statistical models has proven challenging. More complex machine learning approaches may offer better performance and insights.

Topical Protease Inhibitor Increases Tumor-Free and Overall Survival in CD4-Depleted Mouse Model of Anal Cancer.

Patients with immunodeficiencies and older age are at an increased risk of anal cancer. Transgenic mice with established high-grade anal dysplasia were treated topically at the anus with the protease inhibitor saquinavir (SQV) in the setting of CD4+ T-cell depletion to mimic immunodeficiency. To ensure tumor development, specific groups were treated with a topical carcinogen (7,12-Dimethylbenz[a]anthracene (DMBA)).

Multilevel Interventions That Protect and Promote Youth Autonomy Could Reduce Depression at Scale.

Depression is a major public health problem among adolescents and preadolescents in the United States. Clinical scientists have spent considerable resources designing and testing depression interventions. Some programs can prevent and reduce depression to a modest degree, while others show null or potentially adverse impacts on youth mental health.

Don't let reflection eat you up!

As dental professionals, reflective practice is considered a key element of learning and development and is therefore encouraged by both dental educational establishments and the regulator. However, following an adverse event, rather than undertaking what is assumed as reflection, and subsequently moving forward with a deeper understanding, many practitioners will ruminate for days/weeks or even months on the situation and internalise the emotional impact. This ruminating process can lead to issues of poor wellbeing and little constructive learning and can ultimately impact on patient care.

Adolescents' beliefs about what symptoms constitute depression: Are more expansive definitions helpful or harmful?

Purpose: What symptoms do people think constitute "depression"? In a mental health literacy framework, knowing more of depression's nine core symptoms (per formal psychiatric diagnostic criteria) is thought to help people identify and seek help for depression. However, the common-sense model of self-regulation suggests that more expansive beliefs about what symptoms constitute an illness may be maladaptive, whereby viewing symptoms as characterizing a disorder predicts greater functional impairment.

Methods: We collected data from = 281 U.

Key Challenges and Potential Strategies for Engaging Youth with Lived Experience in Clinical Science.

Centering the perspectives of youth with lived experience (YWLE) in psychopathology is critical to engaging in impactful clinical research to improve youth mental health outcomes. Over the past decade there has been a greater push in clinical science to include community members, and especially community members with lived experience, in all aspects of the research process. The goal of this editorial is to highlight the need for and importance of integrating YWLE into every stage of clinical science research, from idea generation to interpretation and dissemination of research findings.

Ecological-Systems Contributors to Internalizing Symptoms in a US Sample of Adolescents During the COVID-19 Pandemic.

Objective: Internalizing problems are common in adolescence and increased substantially during the COVID-19 pandemic. Although rates of anxiety and depression have since improved, the general increase in the prevalence of mental health problems and disruptions to mental health services during the COVID-19 pandemic has resulted in huge gaps in care. Although research has primarily focused on proximal correlates of internalizing problems, a growing literature suggests that factors outside youths' immediate microsystems are equally crucial for their mental well-being.

Evaluating a treatment selection approach for online single-session interventions for adolescent depression.

Background: The question 'what works for whom' is essential to mental health research, as matching individuals to the treatment best suited to their needs has the potential to maximize the effectiveness of existing approaches. Digitally administered single-session interventions (SSIs) are effective means of reducing depressive symptoms in adolescence, with potential for rapid, large-scale implementation. However, little is known about which SSIs work best for different adolescents.

Timing of childhood adversities and self-injurious thoughts and behaviors in adolescence.

Greater childhood adversity predicts a higher likelihood of later self-injurious thoughts and behaviors (SITB). There is little research focused on whether the timing of childhood adversity predicts SITB. The current research examined whether the timing of childhood adversity predicted parent- and youth-reported SITB at age 12 and 16 years in the Longitudinal Studies of Child Abuse and Neglect (LONGSCAN) cohort ( = 970).

Using National Survey Data: A Cross-Sectional Analysis of Surveys with Questions on Chronic Diseases and Social Determinants of Health.

Surveys are a common tool utilized by organizations and researchers to collect data and evaluate various populations. This project aimed to consolidate a list of national health surveys to make the data source identification process easier when utilizing survey data. A cross-sectional analysis of currently available national survey data was conducted using information from the Office of the Assistant Secretary for Planning and Evaluation U.

Brief Interventions for Self-injurious Thoughts and Behaviors in Young People: A Systematic Review.

Rates of self-injurious thoughts and behaviors (SITBs) increase sharply across adolescence and remain high in young adulthood. Across 50 years of research, existing interventions for SITBs remain ineffective and inaccessible for many young people in particular need of mental healthcare. Briefer intervention options may increase access to care.

Improving dental student confidence through the use of simulated patient cases.

Introduction: This study investigates whether student confidence could be improved through the use of simulated patient case-based scenarios.

Materials And Methods: Students in their 4th and 5th year of undergraduate study completed an online e-portfolio workbook consisting of activities related to five simulated patient cases. Following completion of the relevant learning activities within the e-portfolio, students then viewed a tutor case presentation video and attended simulated clinic sessions to complete corresponding exercises involving 3D-printed teeth related to the case.

The Promise of Digital Mental Health for LGBTQ+ Youths.

Lesbian, gay, bisexual, transgender, queer, plus (LGBTQ+) youths face increased risk for psychiatric morbidity, and the stress of being in a minority group drives this disparity. Affirmative treatments can improve mental health among LGBTQ+ youths, but barriers are encountered in accessing care. Digital mental health offers the opportunity to increase access, therefore potentially reducing mental health disparities.

The Transdiagnostic Origins of Anxiety and Depression During the Pediatric Period: Linking NIMH Research Domain Criteria (RDoC) Constructs to Ecological Systems.

In the last decade, an abundance of research has utilized the NIMH Research Domain Criteria (RDoC) framework to examine mechanisms underlying anxiety and depression in youth. However, relatively little work has examined how these mechanistic intrapersonal processes intersect with context during childhood and adolescence. The current paper covers reviews and meta-analyses that have linked RDoC-relevant constructs to ecological systems in internalizing problems in youth.

Structural Correlates of Mental Health Support Access among Sexual Minority Youth of Color during COVID-19.

Many youth with mental health needs cannot access treatment, with multiply-marginalized youth, such as sexual minority youth of Color (SMYoC), experiencing both structural and identity-related barriers to care. The COVID-19 pandemic threatens to exacerbate multi-level treatment access barriers facing SMYoC youth nationwide. However, little large-scale research has examined access to mental health care among SMYoC across the United States, either during or prior to the pandemic.