Publications by authors named "Kathryn E Livingston"
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Synopsis of recent research by authors named "Kathryn E Livingston"
- Kathryn E Livingston's research primarily focuses on the pharmacological properties and therapeutic potential of opioid receptors, particularly through the development of positive allosteric modulators (PAMs) that promise safer analgesic options compared to traditional opioids.
- Her studies emphasize exploring the differential efficacy of various agonists on the mu-opioid (MOR) and delta-opioid (DOR) receptors, shedding light on how biased signaling might improve therapeutic outcomes while minimizing side effects related to pain management and depression.
- Livingston's findings advocate for the potential of allosteric modulation as a strategy to enhance receptor selectivity and efficacy, paving the way for innovative drug development aimed at treating chronic pain and related disorders without the risks associated with conventional opioid therapies.