Reply to: "Nicotine or tobacco abstinence?".

https://bit.ly/3Dn4riC

E-cigarettes and nicotine abstinence: a meta-analysis of randomised controlled trials.

Objectives: To determine the effects of electronic cigarettes (e-cigarettes) as a therapeutic intervention compared to nicotine replacement therapy (NRT) on nicotine abstinence.

Methods: Two authors independently searched the PubMed, Embase, PsycInfo and Cochrane Central Register of Controlled Trials databases for articles published up to and including 10 July 2021. We included randomised controlled trials (RCTs) in which nicotine e-cigarettes were compared to NRT among current cigarette users.